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Liver pathologies can also limit the storage of vitamin B12 in the blood and cause a deficiency
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Using a combination of X-ray crystallography and LO-NMR methods, we identified fragments binding in both the leucine and phenylalanine binding pockets of the TIN2 binding site, two sites crucial for TIN2 TBM engagement with TRF1 TRFH through the F-X-L-X-P motif 15
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