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Rational combinations with orthogonal metabolic agents can be explored, with careful endpoint alignment and safety monitoring
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Color:21 Pink Gold Beige Refill
The intrinsic apoptotic pathway is mainly activated by ROS, which induces opening of the mitochondrial permeability transition pore [70,71], which may cause the release of proapoptotic molecules, such as cytochrome c (an intermembrane space protein), to the cytosol
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