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Recent studies have highlighted key molecular targets such as SREBP (Yue et al., 2021), AMPK (Lu et al., 2016), NF-κB (Ren et al., 2020) as mechanisms by which Chinese botanical drugs regulate lipid metabolism in the liver
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For context, retatrutide vs semaglutide data shows retatrutide producing roughly 50% more weight loss than the highest approved semaglutide dose
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