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A study comparing the anti-HBV effects of different alkaloids showed that HepG2.2.15 cells exposured to 0.4 or 1.6 mM sophocarpine had more effective decreases in hepatitis B surface antigen (HBsAg) levels in the medium than did those exposed to sophoridine or lamivudine, and sophocarpine produced the greatest reduction in HBsAg levels after 24 h of exposure

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doi: 10.1590/S1516-44462011000400003