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Furthermore, some evidence indicates that BDNF could play pro-inflammatory actions, instead of neurotrophic effects, during neuropathic pain [70], a fact that might support the suppressive activity of cortistain in neuroinflammatory response in the injured nerve at the central and peripheral level

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Two other UIM-containing endocytic proteins, Hrs and Hbp, also interact with ubiquilin in a UIM-dependent manner, whereas epsin does not