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Topotecan, a new topoisomerase I (Topo I) inhibitor, has significant activity in patients with chronic myelomonocytic leukemia (CMML)

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Both iron accumulation and oxidative stress have long been linked to the progressive loss of dopaminergic neurons in PD patients, with dopaminergic neuron loss potentially further triggering ferroptosis (Thapa et al., 2022)

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