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In contrast, in the method of Ehlert, the concentration-response curve of the agonist is measured before and after removing any receptor reserve with an irreversible antagonist

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Therapeutic effects in patient-derived osteosarcoma xenograft mouse model For a better understanding of the clinical potential, its therapeutic properties were assessed in a patient-derived osteosarcoma xenograft mouse model (PDX OS ) in immunodeficient nude mice (protocol for model establishment: Fig