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Ongoing Follow-Up Periodic check-ins allow the provider to review response, answer questions, and adjust the overall wellness plan when appropriate

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The importance of HO-1 in tissue protection has also been demonstrated in patients with HO-1 genetic deficiencies that exhibit damage to the liver, kidneys, and vasculature as a result of heme and iron accumulation (70), and in murine models in which HO-1 deficiency leads to high levels of circulating heme and inflammation (71)