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Although it’s often spoken about as “one thing,” its consequences look different depending on the organ system involved: Metabolic organs (liver, adipose tissue, pancreas): Chronic inflammation here is associated with insulin resistance, higher glucose, and fatty liver disease.³⁴ Blood vessels / cardiometabolic system: Inflammation contributes to long-term cardiovascular risk, and GLP-1 therapies improve several cardiometabolic risk factors, including blood pressure.⁶ Kidneys: Metabolic stress accelerates kidney damage and albuminuria