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Symptomatic unstable hemoglobins tend to be β-globin variants, because sporadic mutations affecting only one of the four α globins alleles would generate only 20–30% abnormal hemoglobin

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Okada K., Tanaka H., Temporin K., et al., “Akt/Mammalian Target of Rapamycin Signaling Pathway Regulates Neurite Outgrowth in Cerebellar Granule Neurons Stimulated by Methylcobalamin,” Neuroscience Letters 495, no

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