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FIGURE 5 The primary source of ROS in the endoplasmic reticulum is the formation of intramolecular disulfide bonds during the maturation of many secreted proteins and membrane proteins
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Hereby, Lf binds to HSPGs on the cell surface, relieves the block of the AKT pathway, and enhances AKT phosphorylation to support the regulation of Ca +2 levels within the cell (Rousseau et al., 2013)
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