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When Huggins was awarded his Prize, the Nobel committee said: Your fundamental discoveries concerning the hormone dependence of normal and neoplastic cells in experimental animals and their immediate practical application to the treatment of human prostatic and breast cancer have already given many years of an active and useful life to patients with advanced cancer over the entire civilized world, patients who would have been lost to all other forms of therapy ( Huggins’ most important discovery was that cancers are not always autonomous, but may be under the control of signals, such as hormones, to grow and survive