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Applicable requirements may address: Starting-water quality Sterilization Bacterial endotoxins Particulate matter Antimicrobial agents Container type and volume Container-closure integrity Labeling Intended route of administration Clinical application Sterile Purified Water Sterile Purified Water is defined by the USP official monograph Sterile Purified Water

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and Canada experience 260,000 water main breaks annually, representing $2.6 billion in annual repair costs