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3.4 Pharmacological treatment of hyperuricemia 3.4.1 Conventional agents and mechanisms of action Pharmacotherapy for hyperuricemia involves multiple mechanisms and drug classes, primarily targeting urate production inhibition, uricosuric effects, and metabolic pathway modulation (Wu D
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These findings are in agreement with the outcomes of previous studies, 14,19 importantly the results of the present study suggest that DUL- mitigates renal tubular injury in the DUL+DOX group, as evidenced by the significantly reduced renal injury markers KIM-1 and NGAL in renal tissue
